Most going second cards are inherently better going first than going second, we just got used to getting no going second support that we make due with what we get.

Most going second cards such as droplet or impermanence are really better going first, if you set them they can be a much bigger asset since you most probably already have several disruptions on the field and having this bonus advantage against opponent chokeholds is incredible, so in reality these 2 cards are much better acting as disruptions going first then trying to break a board which is usually almost impossible with modern meta decks. Even hand - traps such as Maxx C or Ash are stronger going first, the worst feeling in the game is someone using Maxx C on you or Ash while they have like 5 negates on their board and you not drawing a proper tool to banish them.